Gene 87634.m00045 (T.vaginalis)

87634.m00045

Species: T.vaginalis
Alias: TvagK0746, 87634.m00045
External Links:
Annotation:

Classification

Group: Other
Family: CAMKK

Sequence

Name Sequence Type Origin Length Description Download
87634.m00045.AA Protein None 340 None Fasta, JSON
87634.m00045.kin_dom Protein Kinase Domain None 269 None Fasta, JSON

Protein domain

Protein domains of 87634.m00045.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 87634.m00045.AA CAMK 73-336 20 2.3e-68 219.18 In-house 1-425 (425) Show / Hide 
Range on Protein: 73-336
Range on HMM: 1-425/425
Sequence Identity: 20% (89 aa)

EIGKGSTTRVYQVLNVETN------------QTYAAKVYSKSLLT------------KQVLLGCN-------SALDNLKEEIEVQSK-------MNNPYV
..|.||   |. . . .|.            | .|.|...|. |.            ..   ...       . ..|.. |||. .|       .. | .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LPIIEIIED-----------EPSD-------SLIMVM---PIAKYG----NLIHYIESQKP----------------DEKNLALCFFQICSAIKYIHSNN
. ..|..||             |.        ..|||     .  |     |  || ....                .|.  . .| |||||..|.||.|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHRDIKPANILVIDVD-----------------NFCLADFSCSRKLSSS-----------------------DEMLLDTKGTPAYLS-PEECSG-----
|||||.|| |||. | .                 |  ..||  ..|. ..                       .... .  |||.| . ||  .|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------DIYSPKATDIWALGLSLYYAMFGYLPFELETT-----------VGSELANLVLNVSHLLKEKELIIPE------------------CSEEVR
          | ....|.|..|  ||    ||.||. ..              .||   ...      .... ..                   .|.|..
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLISKLLVKDYRDRITIEEALNHPWF
|||.|.|..|  .|.|||..|||||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
S_TKc 87634.m00045.AA S_TKc 68-336 27 1.4e-67 231.72 SMART 1-231 (231) Show / Hide 
Range on Protein: 68-336
Range on HMM: 1-231/231
Sequence Identity: 27% (78 aa)

YMFQDEIGKGSTTRVYQVLNVETNQTYAAKVYSKSLLTKQVLLGCNSALDNLKEEIEVQSKMNNPYVLPIIEIIEDEPSDSLIMVMPIAKY--GNLIHYI
| . ..||||.  .||.. ...|.. .| |. .                .... ||.. .| . |..  ......|   |.| |||  .    |.| .||
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYI

ESQKP-------DEKNLALCFFQICSAIKYIHSNNIVHRDIKPANILVIDVDNFCLADFSCSRKLSSSDEMLLDTKGTPAYLSPEECSGDIYSPKATDIW
.....       .|   .  . |||.|..|.||..|.|||.||.|||. .  .  ..||  .|.|           ||| |..|| .    |.... |.|
KKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWW

ALGLSLYYAMFGYLPFELETTVGSELANLVLNVSHLLKEKELIIPECSEEVRDLISKLLVKDYRDRITIEEALN-------HPWF
..|  ||  . || ||.       .. ....                |.|..|.|.|.|.|| ..|.|. |||.       ||||
SCGCILYEMLCGYPPFP----QMQMMFKKIG----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase 87634.m00045.AA Pkinase 68-336 24 2.4e-59 208.28 Pfam 1-293 (293) Show / Hide 
Range on Protein: 68-336
Range on HMM: 1-293/293
Sequence Identity: 24% (76 aa)

YMFQDEIGKGSTTRVYQVLNVETNQTYAAKVYSKSLLTKQVL-----LGCNSALDNLKEEIEVQSKMNNPYVLPIIEIIEDEPSDSLIMVMPIAKYG---
| .   ||.||  .||.  .. |....| |. .|.   ....     |           ||..  ..| |... .... ||  .|.. |||. .  |   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL----------SEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYV

-NLIHYIE---SQKP--DEKNLALCFFQICSAIKYIHSNNIVHRDIKPANILVIDVDNF----CLADFSCSRKL-SSSDEMLLDTKGTPAYLSPEECSGD
  | .||.   . .   .|. .  .. ||.....|.||..|.|||.||.|||. . ..     ...|| .....   ... . .  ||| |..|| . |.
MDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGG

IYSPKATDIWALGLSLYYAMFGYLPFELET----TVGSELANLVLNVSHLLKEKELIIPECS-----------------EEVRDLISKLLVKDYRDRITI
 | ... |.|..|. ||. ..|..||  .     .  .... .... .  |.. .    . |                 || .|.|...| ||  .|.|.
QYYGPKVDMWSCGCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTA

EEALNHPWF
|..|.||||
EQILQHPWF
Kinase 87634.m00045.AA Ciliate-E2 68-336 21 9.4e-58 196.82 In-house 1-365 (365) Show / Hide 
Range on Protein: 68-336
Range on HMM: 1-365/365
Sequence Identity: 21% (84 aa)

YMFQDEIGKGSTTRVYQVLNVETNQTYAAKVYSKSLLTKQ-------------VLLGCNSALDNLKEEIEVQSKMN----------------NPYVLPII
| |.  ||.|.   ||.. . .... .| |.    .. ..             .    .. . ..| || .  ..|                .|... ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQ-QRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMY

EIIEDEPSDSLIMVMPIAKYGNLIHYIESQ------------KPDEKNLALCFFQICS---------------AIKYIHSNN-IVHRDIKPANILVIDVD
|  ...  ... .||  ...|.| .||...            ...||  .  . ||..               |..|.||.| |.|||||| |||.    
ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

NFCLADFSCSRKLSSSDE---------MLLDTK-----------------------GTPAYLSPEECSG--------DIYSPKATDIWALGLSLYYAMFG
  ...||  |.|.. . .         .... |                       ||| |..||  .|          .  .. |||.||  ||. .||
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

YLPFELETTVGSELANLVLNVSHLLKEKELIIP-------------------ECSEEVRDLISK----LLVKDYRDRIT-IEEALNHPWF
..||                     |.... .|                   ..|.|. |||.|    .|.||   ||| .|..||||||
KPPF-----------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 87634.m00045.AA CAMKK 68-336 23 5.2e-57 179.27 In-house 1-396 (396) Show / Hide 
Range on Protein: 68-336
Range on HMM: 1-396/396
Sequence Identity: 23% (95 aa)

YMFQDEIGKGSTTRVYQVLNVET-NQTYAAKVYSK-----SLLTKQVLLGCN----------------SALDNLKEEIEVQSKMNNPYVLPIIEIIEDEP
| ...|||.|.   | .. | .. .. || |...|      |. ||..   .                ...|....||..  |.|.|..   .|.|.|. 
YELMKEIGQGQFGKVKLAYNEYDTQKHYAIKIFNKKYVFKKLKKKQQFYRDPPKRMTNMNQNGEMQMMNPFDCVYQEIAIMKKCNHPNIVKLYEVIDDPQ

SDSLIMV-MPIAKYGNLIHYIESQKPDEKNLA--------------------LCFFQ----------------------------ICSAIKYIH-SNN--
.|.. || |  ...| ..  ... |.| .                       ... |                            .. ...|.| ...  
NDKIYMVQMEYCERGQIMW-WPYWKQDYQPNWPYQYTELYSNRQYQNKDFSIMSEQQSISEFINQVVKQDQYFIHEDYAWKYFRDCIKGLEYLHNYQKAC

-----------------IVHRDIKPANILVIDVD---NFCLADFSCSRKLSSSDEMLLD-----------TKGTPAYLSPEECSG-D-------------
                 |.|||||| |||. . .   .. .|||. | .....|. | .           | ||||.. || ||  .             
SYIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVSHIFEGQDQTLSNCESCFQRELNKTAGTPAFMAPELCSKENQKENYNGYKYRFR

-IYSPKATDIWALGLSLYYAMFGYLPFELETTVGSELAN---LVLNVSHLLKE-KELII------PECSEEVRDLISKLLVKDYRDRITIEEALNHPWF
 ||. || |||||| .||.  || .||  ..    .| .     .| .   .| ||         ||.||.  ||| ..| |.  .||||.. ..|||.
FIYCGKAADIWALGVTLYCFVFGKCPFWHNNLM--QLHHNYMKIKNDPIKFPENKEMLNNVSIYCPEISEDLKDLIKRMLEKNPTKRITIPQIKVHPWV
Kinase 87634.m00045.AA ULK 68-336 26 2.6e-56 193.4 In-house 1-324 (324) Show / Hide 
Range on Protein: 68-336
Range on HMM: 1-324/324
Sequence Identity: 26% (87 aa)

YMFQDEIGKGSTT-RVYQVLNVET---NQTYAAKVYSKSLLTKQVLL--GCNSALDNLKEEIEVQSKMN---NPY--VLPIIEIIEDEPSDSLIMVMPIA
|   ...||||    ||.  |..|   || .|.|. .|. . |. ..  | . ....|| ||... |..   .|.  .   ... |.  .. . ..|   
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEG-QYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYC

KYGNLIHYIESQKP----------DEKNLALCFFQICSAIKYIHSNNIVHRDIKPANILVIDVDN------------FCLADFSCSRKLSSSD---EMLL
  |.| .||. .|.           |.     | |||.. |..|..||.||||||.|||. . .             . .|||  .... . .    |. 
NGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

DTK------GTPAYLSPEECSGD----IYSPKATDIWALGLSLYYAMFGYLPFELE-TTVG----SELAN---LVLNVSHLLKEKELIIP------ECSE
 ..      ||| | .|.  .|      |. . .||| ||  .|.  .|. ||.   ..      ... |          . | . . .|       .|.
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQ----QIYIKNQPIQFPKPPKDPKISP

EVRDLISKLLVKDYRDRITIEEALNHPWF
|..|||...|..| .|||..|| .|||||
ECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 87634.m00045.AA ULK 68-336 26 1.3e-55 191.1 In-house 1-329 (329) Show / Hide 
Range on Protein: 68-336
Range on HMM: 1-329/329
Sequence Identity: 26% (86 aa)

YMFQDEIGKGSTTRVYQVLNVET----NQTYAAKVYSKSLLTKQVLL--GCNSALDNLKEEIEVQSKMN--------NPYVLPIIEIIEDEPSDSLIMVM
|   ...||||  .||.  |..|    |. .|.|. .|. . ..  .  | . ... || ||... |..        .|..   ... |.  .. . ..|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEG-QYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIM

PIAKYGNLIHYIESQKP-----------DEKNLALCFFQICSAIKYIHSNNIVHRDIKPANILVIDVDN------------FCLADFSCSRKLSSS---D
     |.| .||. .|.            |.     | ||... |..|..||.||||||.|||. . .             . .|||  .......   .
EYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQ

EMLLDTK------GTPAYLSPEECSGD----IYSPKATDIWALGLSLYYAMFGYLPFEL--ETTVGSELANLVLNVSHL---LKEKELIIPE------CS
.|.. ..      ||| | .|.  .|      |. . .||| ||  .|.  .|. ||.   ....   . .|. | . .    | . | .|       .|
QMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

EEVRDLISKLLVKDYRDRITIEEALNHPWF
.|..|||...|..| .|||..|| .|||||
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 87634.m00045.AA Ciliate-E2-Unclassified 68-336 23 1.4e-53 184.22 In-house 1-352 (352) Show / Hide 
Range on Protein: 68-336
Range on HMM: 1-352/352
Sequence Identity: 23% (84 aa)

YMFQDEIGKGSTTRVYQVLNVETNQTYAAKVYSKSLLTKQVLLGCNSALDNLKEEIEVQSK------------------MNNPYVLPIIEIIEDEPSDSL
| ..  ||.|.   ||.. . ...  |.|. | |.   . ...  |.  . . |..|...|                  ...|...  ... .|.  . .
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDK--QNI

IMVMPIAKYGNLIHYIESQKP------------------DEKNLA-----LCFFQICSAIKYIHSNN-IVHRDIKPANILVIDVD---NFCLADFSCSRK
..||  ...|.|. ||...|                   .|.. .       | ||.....|.|..| |.|||||| |||. .     . ...||. |.|
YIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKK

LSSS---------------DEMLLDTKGTPAYL----SPEECSGDIYSP---KATDIWALGLSLYYAMFGYLPFELETTVG--------------SELAN
. ..               ..|. .. ||| |.    .||   |  |.    .. |||.||  ||. .|||.||. ..                 ..| .
YQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQ

LVLNVSHLLKEKEL--IIPECSEEVRDLIS----KLLVKDYRDRITIEEALNHPWF
  ..     .. .   |    |.|. |.|.    |.|.|.   |||.|..||||||
NIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 87634.m00045.AA CAMKL 68-336 27 4e-51 161.31 In-house 1-297 (297) Show / Hide 
Range on Protein: 68-336
Range on HMM: 1-297/297
Sequence Identity: 27% (84 aa)

YMFQDEIGKGSTTRVYQVLN-VETNQTYAAKVYSKSLLTKQVLLGCN-------SALDNLKEEIEVQSKMN---NPYVLPIIEIIEDEPS----DSLIMV
| . ...||||   |   ..   |.. .| |.. |. ...     .|       | . ... ||. ....|    | .  . |.||..      . . .|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

MPIAKYGN--LIHYIESQ-----KPDEKNLALCFFQICSAIKYIHSNNIVHRDIKPANILVIDVD--NFCLADFSCSRKLSS----SDEMLLDTKGTPAY
|  .  |.  | .||...     . .|.     | ||.||..|.||..|||||||| |||. . .  |  ..||  | .       ....|    |.|.|
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

LSPEECSG--DIYSPKATDIWALGLSLYYAMFGYLPFELETTVGSELANLVLNVSHLLKEKELIIP---ECSEEVRDLISKLLVKDYRDRITIEEALNHP
 .|| ..|  . |  ...|||..|  ||  ..|||||. .|      .. . .  .  ..    .|   . | ..||||.|.|...  .|.||.. .|||
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYN-KQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHP

WF
|.
WM
Kinase 87634.m00045.AA AGC 68-336 20 4.5e-48 121.25 In-house 1-395 (395) Show / Hide 
Range on Protein: 68-336
Range on HMM: 1-395/395
Sequence Identity: 20% (82 aa)

YMFQDEIGKGSTTRVYQVLNV------ETNQTYAAKVYSKSL--------LTKQVLLGCNSALDN---LKEEIEVQSKMN----------NPYVLP-IIE
. |   |||||  .||.|  .       |.. || || .|.           ....  .  .  .   ..|| .. .|.|          .|..      
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHW-KQ-DQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHY

IIEDEPSDSLIMVMPIAK----------YGNLIHYIE---SQKPDEKNLALCFFQ--------ICSAIKYIHS-NNIVHRD-IKPANILVIDVDNFCLAD
  .|.  . | .||  ..           . | ...     ..  . . |  ..         |..|. |.|| ..|.||| .|| |||  .  . .|.|
SFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTD

FSCSRKLSSSD--------------------------------------------------EMLLDTKG--TPAYLSPEECSGDIYSPKATDIWA--LGL
|  . .. ...                                                  ..     |  || |..||      |. || |.|.  || 
FGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YG-KACDWWSFGLGC

SLYYAMFGYLPFELETTV--------GSELANLVLNVSHLLKEKELII----------PECSEEVRDLISKLLVKDYRDRIT----------IEEALNHP
 .|  ..|| ||  ....          |. ....|    ...|. .           .. |.| .|||.|||.|| ..|..          .||  |||
LMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHP

WF
||
WF
Kinase 87634.m00045.AA CAMKK-Unclassified 181-336 27 3.8e-41 131.59 In-house 186-392 (392) Show / Hide 
Range on Protein: 181-336
Range on HMM: 186-392/392
Sequence Identity: 27% (60 aa)

QICSAIKYIHSNN---------------------IVHRDIKPANILVIDVDN-----FCLADFSCSRKLSSSDEM-LLDTKGTPAYLSPEECSGD--IYS
|.| ...|.| .|                     |.|||||| |||  . ||     | .|||. | .......  | .. ||.....|| .|     | 
QCCKGLQYMHNFNQACSYIIIYINEFDKIDHFQDIIHRDIKPQNILIDHEDNDKGEHFKIADFGISVIMEHEQQKKLKNNAGTYCFMAPEFWSKENFKYD

PKA-------------------------TDIWALGLSLYYAMFGYLPFELETTVGSELANLVLNVSHLLKEKELIIP-----ECSEEVRDLISKLLVKDY
...                          |||.|| ..|.  .. |||  ..    || .       ... ||.  |     .||.|  ||| |.. |. 
YNDYSFLPGTFNPLRKTYRIERICFYKKADIWSLGVTFYCMVYHSLPFWHKNLQ--ELFH------QMICQKEINFPPQYHPHCSHEFKDLIQKMCDKNP

RDRITIEEALNHPWF
 .||||.  |.||||
KKRITIDQMLVHPWF
Kinase 87634.m00045.AA STE 68-336 20 4.7e-37 128.4 In-house 1-359 (359) Show / Hide 
Range on Protein: 68-336
Range on HMM: 1-359/359
Sequence Identity: 20% (75 aa)

YMFQDEIGKGSTTRVYQVLNV------ETNQT---------YAAKVYS------------KSLLTKQVLLGCNSALDNLKEEIEVQSKMN--NPYVLPII
. ....||||..  ||. .|.      .|...         .| |. .            .   .  .    .. ......||.. .|.|   |..   .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQEN-Q-E--LENKNHEEMQQILKEIKIMKKCNHMHPNIVKYY

EIIEDEP-----SDSLIMVMPIAKYGNLIHYIE----SQKPD-----------EKNLALCFFQICSA-IKYIHSNNIVHRDIKPANILVIDVDNFCLADF
   ..|       |.| ..|    .| |   |.     .||.           |. .|   .||. .  .|.||..|.||||||||||.       |.||
GCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDF

SCSRKLSSS----------------DEMLLDTKGTPAYLSPEECSGDI------YSPKATDIWALGLSLYYAMFGYLPFELETTVGSELANLVLNVSHL-
 .. .|..|                ...     ||| . .||  ...       |. |. ||| ||. .     |  |.  ..     .. .  ....  
GVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKC-DIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQ

------LKEKELIIPE--------------------CSEEVRDLISKLLVKDYRDRITIEEALN--HPWF
      ....   .|.                    .|.| .| |.| |.||...| | .. |.  ||..
FEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 87634.m00045.AA TyrKc 68-336 18 1.1e-13 -1.34 SMART 1-280 (280) Show / Hide 
Range on Protein: 68-336
Range on HMM: 1-280/280
Sequence Identity: 18% (54 aa)

YMFQDEIGKGSTTRVYQVLNVETNQTYAAKVYSKSLLTKQVLLGCNSALDNLKEEIEVQSKM--NNPYVLPIIEIIEDE-----PSDSLIMVMPIAKYGN
  . ...| |   .||.       .. | |.  ..             .  . .|... .|   ..| .. .. .. ..      .. | .||  ...|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGD

LIHYIESQK--PDEKNLALCFFQICSAIKYIHSNNIVHRDIKPANILVIDVDNFCLADFSCSRKLSSS-------DEMLL----DTK--GTPAYLSPEEC
| .|. . .     | |    .||..   |.||.|..|||.   |.|| .      .||  ||.. .        |        ..|       ..||  
LKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

SGDIYSPKATDIWALGLSLY-YAMFGYLPFELET---TVGSELANLVLNVSHLLKEKELIIPE-----CSEEVRDLISKLLVKDYRDRITIEEALNHPWF
   ....| .|.|. |  ..    .|  | . ..      .|. ..| .   . . ..    .     |..|. .....    |  || | .|   |  |
NYGKFTTK-SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY--PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 87634.m00045.AA CAMKK-Unclassified 68-162 24 3.8e-09 25.62 In-house 1-110 (392) Show / Hide 
Range on Protein: 68-162
Range on HMM: 1-110/392
Sequence Identity: 24% (27 aa)

YMFQDEIGKGSTTRVYQVLNVETN-----QTYAAKVYSKSLLTKQVLLGCNS--------ALDNLKEEIEVQSKMNNPYVLPIIEIIEDEPSDSLIM--V
| | |..| ||   | ....  |.     . .| ||. |..| | ..    .        .|.....||..  |...|..    |.|.|.  | . |  |
YEFLDKLGRGSFGKVKLATRRYTTDDGVQKQFAIKVFKKQKLKKKKFIYNDNAFTMKMKNRLHLVQQEIAIMKKLWHPNICKLYEVIDDPDNDKIYMGQV

MPIAKYGNLI
|  ...| ..
MEYCQMGQIM
Kinase 87634.m00045.AA Pkinase_Tyr 111-199 20 7.3e-07 23.86 Pfam 39-137 (270) Show / Hide 
Range on Protein: 111-199
Range on HMM: 39-137/270
Sequence Identity: 20% (20 aa)

GCNSA---LDNLKEEIEVQSKM-NNPYVLPIIEIIE--DEPSDSLIMVMPIAKYGNLIHYIESQ-----KPDEKNLALCFFQICSAIKYIHSNNIVHRDI
|. .    .. . .|... ... ..| ..  . ..   .||. ....||. ...|.| .|  ..     ... | |    .||...  | .|.|..|||.
GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-QIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL