LRRI_a-1

Species: S.moellendorffii
Alias: LRRI_a-1
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRRIa

Sequence

Name Sequence Type Origin Length Description Download
LRRI_a-1.AA Protein None 888 None Fasta, JSON
LRRI_a-1.NA RNA None 2667 None Fasta, JSON
LRRI_a-1.kin_dom Protein Kinase Domain None 203 None Fasta, JSON

Protein domain

Protein domains of LRRI_a-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRR_1 LRRI_a-1.AA LRR_1 420-442 29 1.050526 6.67 Pfam 1-26 (26) Show / Hide
Range on Protein: 420-442
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

RIIELNLSS-S--GLKGTISLS-ITKL
.. .|.||.     | |.|. | . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRRI_a-1.AA LRR_1 444-465 33 0.002008 16.31 Pfam 1-26 (26) Show / Hide
Range on Protein: 444-465
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

HLTKIYLDN-N--ALTGRVPD--FSSL
.|....|.. |   ||| .|.  | .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL

Kinase LRRI_a-1.AA TKL 599-864 22 5.8e-64 218.8 In-house 1-364 (364) Show / Hide
Range on Protein: 599-864
Range on HMM: 1-364/364
Sequence Identity: 22% (84 aa)

IGEGSFGPVYYGCLPN---------GVEVAVKVLSSNSKQGY---------------------------QEFQTEIDILSVVHHKNLVPFLGYCTQKSK-
||.|.|| || | . .         | .||||...|.. .                             ...  || ..|  .| |.|.|.|||.. .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------LILVYEFLSNGTLREHLYGEGKRYPTLSWKTRLGIALDAAQGLEYLHT----SCNLH--IIHRDVKTSNILLSFDMV-----------
            | .|.|. ..|.|...|           |  |. .|||.|.|..|||.    .|     ||||| |..|||.  ..            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCT-KPPIIHRDLKSKNILVDENWTNVSNYMYNPNA

---AKVSDFGLSKFYD---SNKASHVSTG--------------IKGTPGYLDPEYHSYS----------------RLTEKSDVYSFGVVLFEIVCGREPL
   .|..|||||.| .   .....  ...              . |||... ||    .                  .||.||||||.||.||.....  
DWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-P

NFTLLEEQIVLS---EWACKELEKGNLRTVIDPSLSD----YGEKAALK-VLEVARKCVERSPHGRPNMSTVVIQL
 . . .......   |.  .   . .||  |.|  ..    . .. ... . . . .| .  |. ||...... .|
YYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase LRRI_a-1.AA IRAK 593-793 34 3.8e-58 199.5 In-house 1-221 (317) Show / Hide
Range on Protein: 593-793
Range on HMM: 1-221/317
Sequence Identity: 34% (77 aa)

SNFKRVIGEGSFGPVYYGCLPNGV-EVAVK----VLSSNSKQGYQEFQT---EIDILSVVHHKNLVPFLGYCTQKSKLILVYEFLSNGTLREHLYGEGKR
..  ..|||| || || | . |    .|||    . ... ..  |.||.   |. ...  .|.|.||..||||. ... |||....||.|.  | . .  
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

YP--TLSWKTRLGIALDAAQGLEYLHTSC-NLHIIHRDVKTSNILLSFDMVAKVSDFGLSKFY--DSNKASHVS-----TGIKGTPGYLDPEYHS--YSR
 |   ||| .|. |.. .| |...||.      |||.|.|..||||  ....| .||||  |    |.| ....       ..||  |. ||.      .
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

LTEKSDVYSFGVVLFEIVCGR
|| |.||||||.|| |.. |.
LTKKTDVYSFGIVLLEVLTGC

Kinase LRRI_a-1.AA Dicty4 594-795 36 1.5e-49 163.46 In-house 2-216 (277) Show / Hide
Range on Protein: 594-795
Range on HMM: 2-216/277
Sequence Identity: 36% (80 aa)

NFKRVIGEGSFGPVYYGCLPNGVEVAVKVL-SSNSK---QGYQEFQTEIDILSVVHHKNLVPFLGYCT----QKSKLILVYEFLSNGTLREHLYG---EG
|.   ||.|||| || |    | |||||.| . | .      .||  |..|..   | |.. |.|.||    ...|.  | |... |.| . |     | 
NIEQRIGKGSFGEVYKGTW-RGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

KRYPTLSWKTRLG---IALDAAQGLEYLHTSCNLHIIHRDVKTSNILLSFDMVAKVSDFGLSKFYDSNKASHV-STGIKGTPGYLDPEYHSYSRLTEKSD
.   .|.| ...    .|.|||.|. .|| .||  ||||| |..|.| . ....||.|||||.     .      .. .|||..  ||     . .||.|
QQSIKLDWPLIKRAMRMAFDAARGMNWLH-CCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKAD

VYSFGVVLFEIVCGREP
||||| ||.||. . ||
VYSFGIVLWEILTRQEP

Kinase LRRI_a-1.AA TKL-Unique 595-790 32 1.4e-48 167.73 In-house 1-222 (290) Show / Hide
Range on Protein: 595-790
Range on HMM: 1-222/290
Sequence Identity: 32% (73 aa)

FKRVIGEGSFGPVYYGCLPNGVEVAVKVLSSNSKQG---YQEFQTEIDILSVVH-HKNLVPFLGYCT----QKSKLILVYEFLSNGTLREHLY------G
|  .||||..|.|| |   .| .||.|... |...     |||  |. .... | |.|.| . |||.    . .....| |... |.|...|        
FWNKIGEGGYGQVYKGKW-RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

EGKRYPTLSWKTRLGIALDAAQGLEYLHTSCNLHIIHRDVKTSNILLSFD-----MVAKVSDFGLSKFYDSNKASHVS-------TGIKGTPGYLDPEYH
  ..  .|... |. .|.|.|||..|||..    ||||| |.||.|.. .     . .|..||||||| ... .. ..       .. .|.. .. ||  
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

SY--SRLTEKSDVYSFGVVLFEIV
.   .  .|||||||||.|| ||.
RMNFCQYSEKSDVYSFGIVLWEIA

Kinase LRRI_a-1.AA TK 593-795 17 1.1e-47 157.48 In-house 1-394 (486) Show / Hide
Range on Protein: 593-795
Range on HMM: 1-394/486
Sequence Identity: 17% (71 aa)

SNFKRVIGEGSFG---PVYYGCLPNG--------------------------VEVAVKVLSSNSKQGYQEFQT-----------------EIDILS--VV
  . ...||| ||    || | . ..                          ..||||.| . . .  .||.                  |. ...  . 
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

HHKNLVPFLGYCTQKSK------------LILVYEFLSNGT----LREHLYGEGKRYPT-----------------------------------------
||.|.| ..|.|||.              ...| |. ..|     ||..|    ..  .                                         
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LSWKTRLGIALDAAQGLEYLHTSCNL----HIIHRDVKTSNILLSFDMV-----------AKVSDFGLS
                               |. ...| .....|.|.|||| |.|     ...|||. . |.|.. ..|           .|..|||||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLH-SKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

K-------FYDSNKASHVSTGIKGTPG-------------------------YLDPEYHS---------YSRLTEKSDVYSFGVVLFEIVC-GREP
.        .. ..   .... .||..                         .. ||            | . |.||||.||||...||.  |.||
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEP

Kinase LRRI_a-1.AA Pkinase_Tyr 594-795 31 2.4e-44 150.83 Pfam 2-214 (270) Show / Hide
Range on Protein: 594-795
Range on HMM: 2-214/270
Sequence Identity: 31% (70 aa)

NFKRVIGEGSFGPVYYGCLP-----NGVEVAVKVLSSNSKQGY---QEFQTEIDILSVV-HHKNLVPFLGYCT-QKSK--LILVYEFLSNGTLREHLYGE
 | ...|||.|| || | .      ....||||.|  .. .     ..|  |. |..   ||.|.| ..| || |.    ...| |.  .| |...|   
TFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKH

--GKRYPTLSWKTRLGIALDAAQGLEYLHTSCNLHIIHRDVKTSNILLSFDMVAKVSDFGLSKFYDSNKASH-VSTG-----IKGTPGYLDPEYHSYSRL
  .|. .|...   |..... |.|.|||.      .||||. . |.|.. ..|.|..||||..    |.    ...|     || ..    ||  .|.. 
REDKQPLTMKD--LLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMA----PECINYGKF

TEKSDVYSFGVVLFEIVC-GREP
|.||||.||||...||.  |..|
TTKSDVWSFGVLMWEIFTYGEQP

Kinase LRRI_a-1.AA TyrKc 593-864 25 3.1e-44 154.19 SMART 1-280 (280) Show / Hide
Range on Protein: 593-864
Range on HMM: 1-280/280
Sequence Identity: 25% (75 aa)

SNFKRVIGEGSFGPVYYGCLPNGVEVAVKVLSSNSKQGYQEFQTEIDILSVV--HHKNLVPFLGYCTQK-------SKLILVYEFLSNGTLREHLYGEGK
  .....||| || || | .   ..||||.| ...    ..|  |. |.. .  ||.|.| ..|.|||.         | .| |. ..| |...|   ..
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

RYPTLSWKTRLGIALDAAQGLEYLHTSCNLHIIHRDVKTSNILLSFDMVAKVSDFGLSKFYDSN------KASHVSTGIKGTPG-----YLDPEYHSYSR
.   |..|. | .....|.| ||||     ..||||  . |.|.. . ..|.||||||.. ..       |   .... ||. .      . ||   |..
K---LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

LTEKSDVYSFGVVLFEIVCGREPLNFTLLEEQIVLSEWACKELEKGNLRTVIDP-----SLSDYGEKAALKVLEVARKCVERSPHGRPNMSTVVIQL
 |.||||.||||...||    ..      ..  .  . . . ...|. .   .      .       .  .. .. ..| .. |. ||..|... ..
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSF-----VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase LRRI_a-1.AA Pkinase 593-795 30 4.9e-44 156.8 Pfam 1-211 (293) Show / Hide
Range on Protein: 593-795
Range on HMM: 1-211/293
Sequence Identity: 30% (66 aa)

SNFKRVIGEGSFGPVYYGCLPNGVE-VAVKVLSSNSKQGYQEFQT-----EIDILSVVHHKNLVPFLGYCTQKSKLILVYEFLSNG----TLREHLYGEG
  ..|.||.|||| || ..  .  . ||||...   ..  .. ||     || |.  ..|.| | ...... |... .| |.. .|     | ... .  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--

KRYPTL--SWKTRLGIALDAAQGLEYLHTSCNLHIIHRDVKTSNILLSFDMVA----KVSDFGLSKFYDSNKASHVSTGIKGTPGYLDPEYHS-YSRLTE
.|. ..  |...   ...  ..||||.|      |||||.| .|||.. ...     |..||||.|..| .  ..  |.. |||.|. || .  ..  . 
WRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGP

KSDVYSFGVVLFEIVCGREP
|.|..|.|..|.| .||| |
KVDMWSCGCILYEMLCGRPP

Kinase LRRI_a-1.AA Dicty5 594-795 33 7.1e-39 131.43 In-house 2-202 (260) Show / Hide
Range on Protein: 594-795
Range on HMM: 2-202/260
Sequence Identity: 33% (69 aa)

NFKRVIGEGSFGPVYYGCLPNGVEVAVKVLSSNS--KQGYQEFQTEIDILSVVH--HKNLVPFLGYCTQKSKL-ILVYEFLSNGTLREHLYGEGK-RYPT
 |  .|  |. | || |   .|  ||.||.|.        .||. |. |.|..   | |.. ..|  ..  |    | |. .||.|.. |    |     
SFHDWIASGASGRVYNGIY-KGMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQP

LSWKTRLGIALDAAQGLEYLHTSCNLHIIHRDVKTSNILLSFDMVAKVSDFGLSKFYDSNKASHVSTGIKGTPGYLDPEYHSYSRLTEKSDVYSFGVVLF
... ..| .|.|.||....|| | |  |||||.|  |.|.  .  .|. ||| | | |  .  |  . . ||. .  .|       ..| ||||||.||.
IAYFQQLHMAIDIAQSMRHLH-SMN--IIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRY--HMTMHV-GTQCWMACELFNGQPYHQKCDVYSFGIVLW

EIVCGREP
|.    ||
EMFTRKEP

Kinase LRRI_a-1.AA MLK 593-795 27 1e-38 131.96 In-house 1-235 (291) Show / Hide
Range on Protein: 593-795
Range on HMM: 1-235/291
Sequence Identity: 27% (67 aa)

SNFKRVIGEGSFGPVYYGCLPNGV----EVAVKVLSSNSKQGYQE-------FQTEIDILSVVHHKN----LVPFLGYCTQK-SKLILVYEFLSNGTLRE
 .|...||.|||| |. |   |      .||||   ..     ..       |..|. .|... |.|     ..|.| |.|  ... .| |....| | .
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

HLYG-EGKRYP---------TLSWKTRLGIALDAAQGLEYLHTSCNLHIIHRDVKTSNILLSF------DMVAKVSDFGLSK-FYDS--NKASHVSTGIK
 |.| ..| ..         . .    . .||. |.|..|||      ||||| | .|||..       ....|..|||.|. ....  |.     .. .
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNM-----MSNA

GTPGYLDPEY---HSYSRLTEKSDVYSFGVVLFEIVCGREP
||. .  ||       .. .||.||.|.|||| |.. ...|
GTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP

Kinase LRRI_a-1.AA Ciliate-E2 593-793 21 2.5e-38 129.17 In-house 1-293 (365) Show / Hide
Range on Protein: 593-793
Range on HMM: 1-293/365
Sequence Identity: 21% (63 aa)

SNFKRVIGEGSFGPVYYGCL---PN------------------GVEVAVKVLSSNSKQGYQEFQTEIDILSVVH----------------HKNLVPFLGY
 .| ..||.|.|| ||...    ..                  .| .  . . ...|.. ...  ||.|.  ..                |.|.. .  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

CT--QKSKLILVYEFLSNGTLREHLY---GEGKRYPT----LSWKTRLGIALDAAQ---------------GLEYLHTSCNLHIIHRDVKTSNILLSFDM
    ..... || |... |.|.....      .  ..    ...| .. |    .|               .|||||   |  ||||| | .|||.    
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN--IIHRDIKPENILF----

VAKVSDFGLSKFYDSN----------------KASHVSTGIK-------------GTPGYLDPEYHSYSR---------LTEKSDVYSFGVVLFEIVCGR
  |..||||||.|| .                   ....|.              |||||. || ...            ..|.|..|.||.|.| ..|.
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK





Kinase LRRI_a-1.AA LRRK 593-795 26 9.9e-38 131.05 In-house 1-282 (351) Show / Hide
Range on Protein: 593-795
Range on HMM: 1-282/351
Sequence Identity: 26% (78 aa)

SNFKRVIGEGSFG-PVYYGCLPN---------------------------GVEVAVKVLSS----------NSKQ------------------------G
  . . ||.|.|| .|| . . .                           . .||.|..            ||                           
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

YQEFQTEIDILSVVHHKNLVPFLGYCTQKSKLILVYEFLSNGTLREHLYGEGKRY-----PTLSWKTRLGIALDAAQGLEYLHTSCNLHIIHRDVKTSNI
..||. |. |.|  .| |.|. .|.| .   |..| |....|.| ..|  . .       . .|| ..| |||. | |.|||| |.|  ||||| |. ||
FREFRHEVWIMSHLNHPNIVSLKGFCIH--PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLH-SHNPPIIHRDLKSPNI

LL-SF-----------DMVAKVSDFGLSK--FYDSNK-ASHVSTGIKGTPGYLDPEYHSY---SRLTEKSDVYSFGVVLFEIVCGR-EP
|| |.           ...||..|||.|   ... .. |.    |  |.||.. ||   |   .  |||.|.||||..|.|.. ..  |
LLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAK----GCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHP

Kinase LRRI_a-1.AA Dicty4-Unclassified 594-795 34 1.7e-37 125.93 In-house 2-207 (263) Show / Hide
Range on Protein: 594-795
Range on HMM: 2-207/263
Sequence Identity: 34% (73 aa)

NFKRVIGEGSFGPVYYGCLPNGVEVAVKVLSSNSKQGY----QEFQTEIDILSVVHHKNLVPFLGYCTQK----SKLILVYEFLSNGTLREHLY-GEGKR
   . ||.| |  |. |    | .|||| . .|. .      |.|  |..||  . | |||   |||       | .. | ||.  |.| |        .
QIDQFIGKGHFSKVHKGNW-KGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQ

YPTLSWKT--RLGIALDAAQGLEYLHTSCNLHIIHRDVKTSNILLSFDMVAKVSDFGLSKFYDSNKASHVSTGIKGTPGYLDPEYHSYSRLTEKSDVYSF
   ..      . .|.| |||. .|||     .||||.| ||||.  .  .|. |||.|   | |      | | |||    ||       . ||||||.
QQPIKLDDTLIIKYAFDIAQGMQHLHT---RNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFN---MTTIAGTPKWESPECLMHESYNQKSDVYSY

GVVLFEIVCGREP
...|.| . | ||
AMMLYELATGDEP

Kinase LRRI_a-1.AA S_TKc 593-868 23 2.5e-35 124.63 SMART 1-231 (231) Show / Hide
Range on Protein: 593-868
Range on HMM: 1-231/231
Sequence Identity: 23% (67 aa)

SNFKRVIGEGSFGPVYYGCLPN-GVEVAVKVLSSNSKQGYQEFQTEIDILSVVHHKNLVPFLGYCTQKSKLILVYEFLSN--GTLREHLYGEGKRYPT--
  . |.||.|.|| || .   . | .||.|...       . .. ||.||.  ||.|.| .....   ..| .| |....  |.|....   |.. .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LSWKTRLGIALDAAQGLEYLHTSCNLHIIHRDVKTSNILLSFDMVAKVSDFGLSKFYDSNKASHVSTGIKGTPGYLDPEYHSYSRLTE-KSDVYSFGVVL
..  .   ..   ...|||.|   ...|||||.| .||||.   . |..||||....         | . ||| |. ||       .  |.|..|.|..|
FPE-HARFYMYQICCALEYCH---SHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

FEIVCGREPLNFTLLEEQIVLSEWACKELEKGNLRTVIDPSLSDYGEKAALKVLEVARKCVERSPHGRPNMSTVVI-----QLREAI
.| .||. |       .. .. .  .                          ...  ||| .. |  ||    .        . . .
YEMLCGYPPFP-----QMQMMFKKIG-----------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase LRRI_a-1.AA MLK 845-864 35 0.00292 7.32 In-house 272-291 (291) Show / Hide
Range on Protein: 845-864
Range on HMM: 272-291/291
Sequence Identity: 35% (7 aa)

KCVERSPHGRPNMSTVVIQL
.| .  || ||... .| .|
QCWNQDPHKRPSFRQIVQHL

Kinase LRRI_a-1.AA TK 841-864 29 0.007473 4.54 In-house 463-486 (486) Show / Hide
Range on Protein: 841-864
Range on HMM: 463-486/486
Sequence Identity: 29% (7 aa)

EVARKCVERSPHGRPNMSTVVIQL
.. ..| .. |  ||..|... ||
DLMQQCWHYDPEDRPTFSQLHEQL

Kinase LRRI_a-1.AA IRAK 824-864 21 0.225582 0.83 In-house 277-317 (317) Show / Hide
Range on Protein: 824-864
Range on HMM: 277-317/317
Sequence Identity: 21% (9 aa)

IDPSLSDYGEKAALKVLEVARKCVERSPHGRPNMSTVVIQL
||.  .. ... ... . .|  |...    |. |  |. ||
IDHRMPPCPPNMEKEMCQCACCCGHHRANRRCDMAWVMQQL