KINASE.COM

The Kinome of Drosophila melanogaster

We cataloged the Drosophila kinome in 2002, and published it along with an evolutionary comparison to yeast, worm, and human kinomes. It included several novel kinases, improved sequences for others, and a detailed classification of the full kinome.

Evolution of protein kinase signaling from yeast to man.
G Manning, GD Plowman, T Hunter, S Sudarsanam (2002)
Trends in Biochemical Sciences 27(10): 514-520. (PDF*)

All of the sequences and classification of these kinases are available through our KinBase database.

* "Reprinted from Trends in Biochemical Sciences, Vol 27(10), G Manning, GD Plowman, T Hunter, S Sudarsanam, Evolution of protein kinase signaling from yeast to man, 514-520, Copyright (2002), with permission from Elsevier Science."